This Ecchi Anime OVA is the Sequel to To Love-Ru: Trouble Series. Based on the To Love-Ru shounen manga written by Hasemi Saki and illustrated by Yabuki Kentarou, serialised in Weekly Shounen Jump.

The daily life of Yuuki Rito, a high school boy, continues, still living with the mysterious alien girl Lala and his sister Mikan under one roof.

Rito has to overcome several hair-raising adventures: Like the strange device that turns him into a girl. Or when he sees his sister Mikan in a state of undress and she runs out of the house, upset. The visit to a quite dangerous holiday resort. The gang's trip into virtual reality, where they have to overcome an outlandish, yet life-threatening quest. To round things off Nana and Momo, Lala's mischievous younger twin sisters drop in for a surprise visit.